At Shankara Cancer Hospitals, the Molecular Diagnostics and Research Department is at the forefront of personalized cancer care, leveraging advanced molecular techniques to deliver precise diagnoses and develop targeted therapies.
Overview
Our dedicated team of specialists and state-of-the-art facilities ensure that patients receive tailored treatment based on the unique genetic makeup of their cancer.
Facilities
Our Molecular Diagnostics and Research Centre is equipped with cutting-edge technology-driven platforms, offering a wide range of molecular and genetic tests to support accurate cancer diagnosis and treatment planning. We provide comprehensive in-house services, ensuring patients receive timely and precise care without needing to travel between different facilities.
- Flow Cytometry and Cytogenetics: Enables detailed cellular analysis, vital for identifying specific cancer types.
- Quantitative Real-Time PCR: Facilitates the quantification of genetic alterations in DNA or RNA sequences, aiding in early cancer detection and monitoring treatment effectiveness.
- Fluorescence In Situ Hybridization (FISH): Detects specific DNA sequences, critical for diagnosing certain types of cancers.
- Sanger Sequencing: A traditional and reliable method for identifying specific point mutations in cancer genes.
- Next Generation Sequencing (NGS): Provides comprehensive genetic analysis to guide targeted therapies.
- Mass Spectrometry: Analyzes proteins and small molecules, essential for biomarker discovery and cancer diagnostics.
- Cell Culture: Supports research and diagnostic studies by allowing cancer cells to be grown and analyzed in a controlled environment.
- Circulating Tumor DNA (ctDNA) Analysis: A non-invasive technique to detect and monitor cancer through blood samples, offering insights into tumour dynamics and treatment response.
The Genetics of Cancer
Our Molecular Oncology Scientists explain the genetics of cancer and how they can help you safeguard yourself from cancer through preventive screening & early detection.
Role of Molecular Diagnostics in Cancer Care
Molecular diagnostics play a pivotal role in modern cancer care by enabling the precise identification of genetic alterations, biomarkers, and intrinsic classification into specific cancer types. This allows for personalised treatment plans tailored to the unique genetic profile of each patient’s cancer. From early detection to monitoring treatment response, molecular diagnostics provide critical insights that guide the use of targeted therapies, minimise side effects, and improve overall patient outcomes. By integrating advanced molecular techniques, Shankara Cancer Hospitals ensures that patients receive the most accurate diagnosis and effective treatments available.
Tests performed
Cytogenetics
- Cytogenetics Bone Marrow - conventional karyotyping
- Cytogenetics Peripheral Blood - conventional karyotyping
- Constitutional Cytogenetics -constitutional karyotyping
- HER2/Neu By FISH
- ALK Rearrangement by FISH
- ROSI Rearrangement by FISH
- EWSR 1 Rearrangement by FISH
- FISH For Triple Hit Lymphoma
- FISH For CLL panel on Blocks
- FISH for any single marker on Blocks
- FISH For Dual Hit Lymphoma
- FISH For Multiple Myeloma
- FISH Panel ALL
- FISH Panel CLL
- FISH Panel AML
- FISH Panel MDS
- FISH FOR MLL rearrangement
- FISH For PML - RARA
- FISH For BCR - ABL
- FISH For Single Marker
Next Generation Sequencing (NGS)
- Comprehensive Pan-Cancer 161 gene test by NGS
- Can Focus Pan-Cancer 52 Gene test by NGS (DNA+RNA)
- HRR Somatic by NGS
- Extended BRCA Panel by NGS
- BASIC BRCA Germline testing panel
- Flex Gene Panel by NGS
- Flex Gene Panel by NGS + PDL 1
- Comprehensive lung Panel (DNA+RNA by NGS + PDL1 by IHC)
- Hereditary Cancer Panel
- MYELOID Panel NGS
- Can Focus - Breast - NGS
- MPN Reflex Panel
Mutation and Translocation Assays by PCR Method
- EGFR Mutation Analysis by ARMS PCR
- KRAS+NRAS+BRAF Mutation Panel by ARMS
- B-RAF Mutation Analysis
- K-RAS Mutation Analysis
- N-RAS Mutation Analysis
- ALK Fusion detection by ARMS
- BCR - ABL Translocation IS-MMR(with breakpoint)
- BCR - ABL Translocation IS -MMR(without breakpoint)
- PML -RARA Quantitative RT - PCR
- Liquid Biopsy - EGFR Mutation testing by ARMS PCR
- Liquid Biopsy - KRAS/NRAS/BRAF Mutation testing by ARMS PCR
- POL - E Mutation Analysis by Sanger
Flow Cytometry
- Flow Cyometry - Lymphoma Panel
- Flow Cyometry - Leukemia Panel
- CD34 Stem cell assay
- B - ALL MRD
- MRD Myeloma Panel by Flow Cytometry
- DNA Ploidy Analysis by Flow Cytometry
- Flow Cyometry - Single tube
- T - ALL MRD
- Flow Cytometry - Myeloma Diagnostic Panel
Immunoassay
- Chromogranin A (EIA)
Sanger Sequencing
- MSI by SANGER Germline/Somatic
- Pre - chimerism
- Post - chimerism
- B AND T cell clonality assay
Experts
Molecular Oncology Scientists transform patient care with their profound expertise, sharp diagnostic precision, and innovative research leading to treatment and turning complex challenges into paths for healing and recovery.
Research
Our cutting-edge research in the field of Molecular Research and Diagnostics Centre at Shankara Cancer Hospitals, drives innovation in cancer treatment and improves our patient outcomes.
Department Level Donors
- ABB
- 3M through United Way Bengaluru
- Vijaya Bank
